Adipose Tissue Biology and Inflammation

Adipose tissue is an active endocrine organ influencing metabolic health through adipokine secretion and immune modulation. In obesity, adipose expansion leads to hypoxia, macrophage infiltration, and chronic low-grade inflammation, creating systemic insulin resistance and organ dysfunction. The interplay between white, brown, and beige adipose tissue highlights the dual roles of fat in energy storage and thermogenesis. Advanced research into inflammatory cascades, cytokine networks, and adipose remodeling provides insights into therapeutic strategies that aim to restore metabolic balance and reduce obesity-related morbidity.

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